abstract：BACKGROUND:In heart failure (HF), changes in lung mechanics and gas diffusion are limiting factors to exercise. Their contribution to an increased exercise ventilation to CO2 production (VE/VCO2) slope is undefined. METHODS:A total of 67 stable HF patients underwent cardiopulmonary exercise and pulmonary function test...

journal_title：European journal of heart failure

authors： Guazzi M,Reina G,Tumminello G,Guazzi MD

更新日期：2005-10-01 00:00:00

abstract：AIMS:Cardiogenic shock is the leading cause of in-hospital mortality after acute myocardial infarction (MI). This study investigates the importance of age and preexisting diabetes mellitus on the incidence and prognosis of cardiogenic shock in a large group of consecutive patients with MI. METHODS AND RESULTS:Baseline...

journal_title：European journal of heart failure

authors： Lindholm MG,Boesgaard S,Torp-Pedersen C,Køber L,TRACE registry study group.

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:In most animal models of chronic hemodynamic overload of the left ventricle (LV) as well as in human end stage heart failure, the sarcoplasmic reticulum (SR) Ca2+-ATPase (SERCA2a) mRNA levels are decreased in parallel with increased atrial natriuretic peptide (ANP) mRNA levels. The situation in the remote my...

journal_title：European journal of heart failure

authors： Prunier F,Chen Y,Gellen B,Heimburger M,Choqueux C,Escoubet B,Michel JB,Mercadier JJ

更新日期：2005-08-01 00:00:00

abstract：:We have documented a pre-junctional beta-2 adrenoceptor mediated reduction in cardiac norepinephrine spillover (CNES) in heart failure patients receiving chronic beta-blockade. Our present objective was to ascertain the consequence of this decrease for vagal heart rate (HR) regulation by determining CNES, arterial bar...

journal_title：European journal of heart failure

authors： Kubo T,Parker JD,Azevedo ER,Atchison DJ,Newton GE,Picton P,Floras JS

更新日期：2005-08-01 00:00:00

abstract：:Patients with mild-moderate chronic heart failure (CHF) often have raised levels of serum uric acid (UA). This is due, amongst other factors, to reduced UA excretion by the kidneys, which is partly explained by restriction of sodium intake and treatment with diuretics. The decline in renal function that parallels wors...

journal_title：European journal of heart failure

authors： Reyes AJ

更新日期：2005-06-01 00:00:00

abstract：:BNP is a marker of systolic left ventricular dysfunction (LVSD) and heart failure. To assess BNP for the detection of diastolic dysfunction in the general population, we examined 1678 subjects within an age- and sex-stratified survey (MONICA Augsburg). BNP was measured using a commercially available RIA (Shionogi). BN...

journal_title：European journal of heart failure

authors： Lukowicz TV,Fischer M,Hense HW,Döring A,Stritzke J,Riegger G,Schunkert H,Luchner A,MONICA Investigators.

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:There is increasing evidence that discharge planning and post-discharge support for CHF patients can contribute greatly to the medical management of heart failure (CHF) in the community and that the quality of the CHF patient's close personal relationships can influence outcome in CHF. However, there has bee...

journal_title：European journal of heart failure

authors： Molloy GJ,Johnston DW,Witham MD

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:New-onset atrial fibrillation (AF) after acute myocardial infarction (AMI) frequently occurs in association with postinfarction complications, particularly with heart failure (HF). AIMS:To evaluate whether postinfarction HF is associated with the subsequent development of AF and whether AF independently pre...

journal_title：European journal of heart failure

authors： Asanin M,Perunicic J,Mrdovic I,Matic M,Vujisic-Tesic B,Arandjelovic A,Vasiljevic Z,Ostojic M

更新日期：2005-06-01 00:00:00

abstract：:Heart failure (HF) in elderly patients is associated with more diffuse symptoms and signs due to the presence of other noncardiac comorbidities. This can cause difficulties in assessing the correct diagnosis and initiating appropriate therapy. The four most frequently occurring noncardiac comorbidities and therapies u...

journal_title：European journal of heart failure

authors： Dahlström U

更新日期：2005-03-16 00:00:00

abstract：AIMS:To determine the effects of a nurse-led intervention designed to improve self-management of patients with heart failure in a primary health care setting regarding health-related quality of life and depression. METHODS:Patients at eight primary health care centres were screened by the Diagnosis Related Groups regi...

journal_title：European journal of heart failure

authors： Mårtensson J,Strömberg A,Dahlström U,Karlsson JE,Fridlund B

更新日期：2005-03-16 00:00:00

abstract：:Ambulatory blood pressure monitoring has established its use in the definition of white coat hypertension and monitoring of treatment of essential hypertension. Any role for ambulatory blood pressure monitoring in heart failure is not well defined. However, from the limited studies available, ambulatory blood pressure...

journal_title：European journal of heart failure

authors： Goyal D,Macfadyen RJ,Watson RD,Lip GY

更新日期：2005-03-02 00:00:00

abstract：:COMBAT is a prospective, multicenter, randomized, blinded clinical study, with crossover design. The main objective is the comparative evaluation of atrio-biventricular versus conventional atrioventricular stimulation (atrio and right ventricle) in patients with heart failure and bradycardia as the primary indication ...

journal_title：European journal of heart failure

authors： Martinelli M,Costa R,de Siqueira SF,Ramires JA

更新日期：2005-03-02 00:00:00

abstract：AIMS:Endothelial dysfunction has been shown to correlate with severity of congestive heart failure (CHF) and recent data suggest morphological changes of peripheral vasculature to be associated with the syndrome. We therefore investigated the hypothesis that vascular remodeling is associated with functional changes in ...

journal_title：European journal of heart failure

authors： Poelzl G,Frick M,Huegel H,Lackner B,Alber HF,Mair J,Herold M,Schwarzacher S,Pachinger O,Weidinger F

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Hereditary hemochromatosis (HH), a common autosomal recessive disease, leads to excessive iron accumulation in some organs, including the heart. It is therefore not surprising that cardiomyopathy is one of the most severe complications of HH. The HFE gene defects have been thought to contribute to idiopathic...

journal_title：European journal of heart failure

authors： Hannuksela J,Leppilampi M,Peuhkurinen K,Kärkkäinen S,Saastamoinen E,Heliö T,Kaartinen M,Nieminen MS,Nieminen P,Parkkila S

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Chronic heart failure (CHF) is a complex syndrome, in which reactive oxygen species and inflammatory cytokines are important stressors that contribute to the pathogenesis. AIM:We have studied physiological stress response parameters in CHF, in particular the redox-active regulator thioredoxin. SUBJECTS:A c...

journal_title：European journal of heart failure

authors： Jekell A,Hossain A,Alehagen U,Dahlström U,Rosén A

更新日期：2004-12-01 00:00:00

abstract：INTRODUCTION:Patients with chronic heart failure (CHF) experience breathlessness and fatigue on exercise. One of the abnormalities seen on maximal exercise testing is an increased ventilatory response to exercise (VE/VCO(2) slope). The cause of this is unknown, but is likely to be due to a combination of interacting pe...

journal_title：European journal of heart failure

authors： Witte KK,Clark AL

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:Chronic heart failure (CHF) is common and is frequently managed by primary care physicians (PCPs). Despite the European Society of Cardiology (ESC) Guidelines, standard treatments for CHF are frequently underutilised, particularly in primary care. AIM:To evaluate current drug therapy for CHF in adults with ...

journal_title：European journal of heart failure

authors： Ceia F,Fonseca C,Mota T,Morais H,Matias F,Costa C,Oliveira AG

更新日期：2004-10-01 00:00:00

abstract：AIMS:Hemochromatosis is a condition in which iron loading impairs the function of many organs, including the heart. Congestive heart failure with left ventricular dilatation is commonly found in patients with hemochromatosis. Two missense mutations (C282Y and H63D) have been shown to be responsible for the majority of ...

journal_title：European journal of heart failure

authors： Goland S,Beilinson N,Kaftouri A,Shimoni S,Caspi A,Malnick SD

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVE:To determine the acute vasodilator effect of sublingual sildenafil in heart transplant candidates with severe pulmonary hypertension due to severe left ventricular dysfunction (LVD). BACKGROUND:Pulmonary hypertension confers an increased risk of early graft failure. PATIENTS AND METHODS:Seven patients, (mea...

journal_title：European journal of heart failure

authors： Angel Gómez-Sánchez M,Saenz De La Calzada C,Escribano Subías P,Francisco Delgado Jiménez J,Lázaro Salvador M,Albarrán González A,Cea Calvo L

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the utility of NT-proBNP in the emergency diagnosis and in-hospital monitoring of patients with acute dyspnoea and ventricular dysfunction. BACKGROUND:Misdiagnosis of heart failure (HF) is common in the urgent care setting using clinical diagnostic tests. Reports show that BNP is useful to diagno...

journal_title：European journal of heart failure

authors： Bayés-Genís A,Santaló-Bel M,Zapico-Muñiz E,López L,Cotes C,Bellido J,Leta R,Casan P,Ordóñez-Llanos J

更新日期：2004-03-15 00:00:00

abstract：:The Elecsys NT-proBNP assay is based on two polyclonal antibodies directed at residues 1-21 and 39-50 of the NT-proBNP molecule. Analytical performance was assessed using NCCLS protocol EP-5A using three serum pools in a preliminary study then as part of a multicentre evaluation (16 instruments in 8 hospitals). Using ...

journal_title：European journal of heart failure

authors： Collinson PO,Barnes SC,Gaze DC,Galasko G,Lahiri A,Senior R

更新日期：2004-03-15 00:00:00

abstract：BACKGROUND:Nuclear factor kappa B (NF-kappaB) is activated by several factors, which increase the inflammatory response, and this activation, in turn, leads to the expression of several genes such as cytokines, and may play an important role in cardiovascular diseases. AIMS:The aim of the study is to examine the effec...

journal_title：European journal of heart failure

authors： Matsumori A,Nunokawa Y,Yamaki A,Yamamoto K,Hwang MW,Miyamoto T,Hara M,Nishio R,Kitaura-Inenaga K,Ono K

更新日期：2004-03-01 00:00:00

abstract：AIMS:To evaluate in patients with heart failure (HF) due to systolic dysfunction the occurrence of polypharmacy, alternative medicine, immunization against influenza, and patients' knowledge about their medication. METHODS AND RESULTS:Sixty-five patients, 49 men, mean age 60.5+/-12.0 years answered a confidential ques...

journal_title：European journal of heart failure

authors： Martínez-Sellés M,García Robles JA,Muñoz R,Serrano JA,Frades E,Domínguez Muñoa M,Almendral J

更新日期：2004-03-01 00:00:00

abstract：AIM:Evaluation of N-terminal pro-brain natriuretic peptide (NT-proBNP) to confirm or disprove heart failure in community patients complaining of dyspnoea. METHODS AND RESULTS:General practitioners referred 345 consecutive patients complaining of dyspnoea to our hospital-based clinic, where a diagnosis was established ...

journal_title：European journal of heart failure

authors： Nielsen LS,Svanegaard J,Klitgaard NA,Egeblad H

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:To investigate in vivo effects of long-term selective beta1-blockade on cardiac energy metabolism, remodelling, function and plasma cytokines in a rat model of post-infarct congestive heart failure (CHF). METHODS:Myocardial infarction (MI) was induced in male rats by ligation of the left coronary artery. Thr...

journal_title：European journal of heart failure

authors： Omerovic E,Bollano E,Soussi B,Waagstein F

更新日期：2003-12-01 00:00:00

abstract：AIMS:To characterise the prevalence, in-hospital complications, management, and long-term outcome of patients with congestive heart failure but preserved left ventricular systolic function after acute myocardial infarction. METHODS:3166 consecutive patients screened for entry in the Bucindolol Evaluation in Acute Myoc...

journal_title：European journal of heart failure

authors： Møller JE,Brendorp B,Ottesen M,Køber L,Egstrup K,Poulsen SH,Torp-Pedersen C,Bucindolol Evaluation in Acute Myocardial Infarction Trail Group.

更新日期：2003-12-01 00:00:00

abstract：:Patients with chronic coronary heart disease often suffer from congestive heart failure (CHF) despite multiple drug therapies. D-Ribose has been shown in animal models to improve cardiac energy metabolism and function following ischaemia. This was a prospective, double blind, randomized, crossover design study, to ass...

journal_title：European journal of heart failure

authors： Omran H,Illien S,MacCarter D,St Cyr J,Lüderitz B

更新日期：2003-10-01 00:00:00

abstract：:This article contains a series of reports on recent research developments in the field of heart failure. Reports of key presentations made at the European Society of Cardiology meeting, held in Vienna, Austria, between 30 August and 3 September 2003 are reported. In the CHARM study, candesartan reduced cardiovascular ...

journal_title：European journal of heart failure

authors： Coletta AP,Cleland JG,Freemantle N,Loh H,Memon A,Clark AL

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Mortality in patients with mild to moderate chronic heart failure remains high. At present there is no easy way of identifying patients within this population at increased risk of death in the medium to long term. AIMS:To develop a prognostic index to identify outpatients with mild to moderate chronic heart...

journal_title：European journal of heart failure

authors： Kearney MT,Nolan J,Lee AJ,Brooksby PW,Prescott R,Shah AM,Zaman AG,Eckberg DL,Lindsay HS,Batin PD,Andrews R,Fox KA

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:There are established differences in cardiovascular disease in different racial groups. Worldwide, the literature regarding the clinical epidemiology of congestive heart failure (CHF) in non-white populations is scarce. OBJECTIVES:To document the prevalence of CHF in the multiracial population of Malaysia, ...

journal_title：European journal of heart failure

authors： Chong AY,Rajaratnam R,Hussein NR,Lip GY

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Cardiac angiotensin converting enzyme (ACE) is activated by an increase in wall stress and is involved in remodeling processes. Heart failure is often treated with ACE inhibitors and diuretics although diuretic treatment could activate the renin-angiotensin system (RAS). AIMS:To examine the effects of diure...

journal_title：European journal of heart failure

authors： Seeland U,Kouchi I,Zolk O,Jockenhövel F,Itter G,Linz W,Böhm M

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVES:To compare the efficacy of the homeopathic Crataegus preparation Cralonin for non-inferiority to standard treatment for mild cardiac insufficiency. METHODS:Multicentre non-randomised cohort study in patients aged 50-75 years in New York Heart Association class II. Patients received Cralonin (n=110) or ACE i...

journal_title：European journal of heart failure

authors： Schröder D,Weiser M,Klein P

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:Biventricular (BiV) pacing has been found to improve systolic function and exercise tolerance in patients with severe congestive heart failure and bundle branch block. The mechanisms behind this beneficial effect is still not sufficiently clarified. AIM:To evaluate the regional myocardial perfusion (MP) dur...

journal_title：European journal of heart failure

authors： Nielsen JC,Bøttcher M,Jensen HK,Nielsen TT,Pedersen AK,Mortensen PT

更新日期：2003-03-01 00:00:00

abstract：:Although no universal definition exists, decompensated heart failure may be regarded as either a worsening of chronic heart failure or new-onset heart failure precipitated by an acute incident. Haemodynamic management of patients hospitalised with decompensated heart failure may include the administration of diuretics...

journal_title：European journal of heart failure

authors： Greenberg B,Borghi C,Perrone S

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND AIM:The choice of optimal treatment strategy in patients with coronary artery disease (CAD) and severe left ventricular (LV) dysfunction is often difficult. The aim of this study was to compare long-term results of patients with chronic CAD, severe heart failure and a defined scope of myocardial viabilit...

journal_title：European journal of heart failure

authors： Meluzín J,Cerný J,Spinarová L,Toman J,Groch L,Stetka F,Frélich M,Hude P,Krejcí J,Rambousková L,Panovský R

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:The angiotensin II type 2 (AT2) receptor is thought to play a role in cardiovascular disorders such as neointima formation after vascular injury, cardiac hypertrophy and myocardial infarction (MI). Recently, the biallelic polymorphism G + 1675A in intron 1 of the AT2 receptor gene has been associated with le...

journal_title：European journal of heart failure

authors： Herrmann SM,Nicaud V,Schmidt-Petersen K,Pfeifer J,Erdmann J,McDonagh T,Dargie HJ,Paul M,Regitz-Zagrosek V

更新日期：2002-12-01 00:00:00

abstract：AIMS:To investigate the annual hospitalization rate and seasonal variation in confirmed heart failure (HF) admissions. METHODS AND RESULTS:Records from all admissions to one hospital during 1 year with a HF diagnostic code were reviewed. From 1953 admissions, 595 were excluded because they did not fulfill the diagnost...

journal_title：European journal of heart failure

authors： Martínez-Sellés M,García Robles JA,Prieto L,Serrano JA,Muñoz R,Frades E,Almendral J

更新日期：2002-12-01 00:00:00

abstract：AIMS:The purpose of this study was to determine that the administration of an angiotensin converting enzyme (ACE) inhibitor enalapril would confer protection against doxorubicin-induced experimental heart failure, and attenuate the development of left ventricular dysfunction. METHODS:Seventeen dogs were chronically in...

journal_title：European journal of heart failure

authors： Vaynblat M,Shah HR,Bhaskaran D,Ramdev G,Davis WJ 3rd,Cunningham JN Jr,Chiavarelli M

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:The rate constant for global fatty acid influx (k(1)) was studied in 12 male patients with dilated cardiomyopathy (DCM). METHOD:10 normal subjects served as controls. 201-Thallium (201TI) and [123I]-phenyl-pentadecanoic acid (IPPA) were administered during bicycle exercise under fasting conditions. RESULTS...

journal_title：European journal of heart failure

authors： Miche E,Radzewitz A,Notohamiprodjo G,Baller D,Kloppe A,Eckert S,Gleichmann U

更新日期：2002-08-01 00:00:00

abstract：UNLABELLED:The aim of this study was to evaluate the efficacy of adding the beta-blocker bucindolol to standard therapy shortly after a myocardial infarction in a high-risk population with reduced left ventricular function. METHODS:The study was planned to include 2000 patients with an enzyme confirmed myocardial infa...

journal_title：European journal of heart failure

authors： Torp-Pedersen C,Køber L,Ball S,Hall A,Brendorp B,Ottesen M,Berning J,Jensen G,Hampton J,Zilles P,Eberle S,Carlsen J

更新日期：2002-08-01 00:00:00